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Welcome to Science Sessions, the PNAS podcast program. Listen to brief conversations with cutting-edge researchers, Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in PNAS, plus a broad range of scientific news about discoveries that affect the world around us. Please scroll down for recent podcasts.

Oct 7, 2024

How python hearts grow and shrink

Science Sessions are brief conversations with cutting-edge researchers, National Academy members, and policymakers as they discuss topics relevant to today's scientific community. Learn the behind-the-scenes story of work published in the Proceedings of the National Academy of Sciences (PNAS), plus a broad range of scientific news about discoveries that affect the world around us.

In this episode, Leslie Leinwand, of the University of Colorado in Boulder, and Claudia Crocini, of Charité – Berlin University of Medicine in Germany, describe how the hearts of constricting pythons change size after meals.

In this episode, we cover:
•[00:00] Introduction
•[01:19] What is the natural context for cardiac hypertrophy in constricting pythons?
•[02:48] What were the mechanisms involved in this process that you identified?
•[05:27] What did you discover about the mechanisms of heart size regression in these snakes?
•[07:24] What are the next steps in this line of research?
•[08:21] Conclusion.

About Our Guest:
Leslie Leinwand
Professor
University of Colorado

Claudia Crocini
Junior Research Group Leader
Charité – Berlin University Medicine

View related content here: https://www.pnas.org/doi/full/10.1073/pnas.2322726121

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